tert-butyl 4-aMinoindoline-1-carboxylate

tert-butyl 4-aMinoindoline-1-carboxylate - Names and Identifiers

Name	1H-Indole-1-carboxylicacid, 4-amino-2,3-dihydro-, 1,1-dimethylethyl ester
Synonyms	tert-butyl 4-aMinoindoline-1-carboxylate tert-Butyl 4-amino-2,3-dihydro-1H-indole-1-carboxylate 4-Amino-2,3-Dihydro-Indole-1-Carboxylic Acid Tert-Butyl Ester 4-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1H-Indole-1-carboxylicacid, 4-amino-2,3-dihydro-, 1,1-dimethylethyl ester 1H-Indole-1-carboxylic acid, 4-amino-2,3-dihydro-, 1,1-dimethylethyl ester 1H-Indole-1-carboxylic acid, 4-aMino-2,3-dihydro-, 1,1-diMethylethyl ester
CAS	885272-42-4

tert-butyl 4-aMinoindoline-1-carboxylate - Physico-chemical Properties

Molecular Formula	C13H18N2O2
Molar Mass	234.29
Density	1.177±0.06 g/cm3(Predicted)
Boling Point	370.4±41.0 °C(Predicted)
pKa	4.19±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

tert-butyl 4-aMinoindoline-1-carboxylate - Introduction

1H-Indole-1-carboxylicacid, 4-amino-2,3-dihydro-, 1,1-dimethylethyl ester is an organic compound whose chemical formula is C12H14F2N2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: white crystal or solid powder
-Melting point: about 125-127 degrees Celsius
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane
-Stability: Stable at room temperature, but may decompose under strong light

Use:
1H-Indole-1-carboxylicacid, 4-amino-2,3-dihydro-, 1,1-dimethylethyyl ester are commonly used as intermediates in organic synthesis reactions. It can be used to prepare indole compounds, nitrogen-containing compounds and bioactive molecules. In addition, it can also be used for research and development in the field of medicine and pesticides.

Preparation Method:
1H-Indole-1-carboxylicacid, 4-amino-2,3-dihydro-, 1,1-dimethylethyl ester can be obtained by acidification of 4-amino-2, 3-difluoroindole-1-carboxylic acid with tert-butyl alcohol. The reaction is typically carried out under an inert atmosphere with the addition of a suitable catalyst and solvent.

Safety Information:
General laboratory safety practices should be followed when using and handling the compound. It can be irritating to the eyes and skin, so contact should be avoided. Appropriate protective equipment, such as gloves and goggles, should be worn during use. If contact or inhalation occurs, wash the affected area immediately and seek medical help.

Last Update：2024-04-09 20:49:11